CD79A and nephrotic syndrome: When serum IgA was combined with the other 2 parameters, particularly manifestation and fibrinogen, the diagnostic accuracy of serum IgA increased from 75.6 to 83.9%, as determined by ROC curve analysis, suggesting that, with the exception of serum IgA, clotting mechanisms might be different in the development of IgAN and non-IgAN, which reflected in the proportion of nephrotic syndrome in IgAN (17.2%) and non-IgAN (52.4%).