Anemia in neonates is defined as more than 2 SD under the mean value of the amount of hemoglobin or HCT for a given age.[1] Anemia of prematurity starts at third or fourth week after birth and the amount of Hb may decrease to 7 g/dl.[2] It sometimes has clinical manifestations like pallor, apnea, no weight gain, decrease in activity, tachypnea, tachycardia and nutritional problems that necessitates blood transfusion.[1][2]. Here, GSTM1 is linked to anemia.