MMP3 and oral lichen planus: A permanent or prolonged presence of high MMP-3 amounts in serum may contribute to malignant transformation of OLP lesions, It is known that MMP-3 has a role in oncogenesis and expressed in OSCC,[20][21] as well as that the erosive/atrophic form of OLP has a greater rate of malignant evolution in comparison with the reticular form.[22]