The frequency of diabetes mellitus is increasing and it is expected that this disorder will affect 300 million people in 2025.[1] It has been suggested that diabetes is an immune dependent disease in which the pattern of cytokine expression is changed.[2] As an example, in type 2 diabetes, the monocytes of peripheral blood produce more inflammatory cytokines than those from normal patients.[2] The association of IL-10 in immunological disorders such as multiple sclerosis,[3][4] nephrotic syndrome[5][6] and type-1 diabetes[7][8] is well established. Here, IL10 is linked to type 2 diabetes mellitus.