CD8A and infection: To verify if type-17 CD8+ TEM cells specific to apoptotic self-antigens in the long run acquire functional plasticity in vivo[15], [18], [27]–[29], we monitored (from the clinical onset of infection up to 24 months) selected patients showing a notable number of CD8+ TEM cells promptly producing IL-17 within few h of contact with the relevant apoptotic epitopes at the clinical onset.