Genes that cause developmental glaucoma [23], with the exception of the cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1) and LIM homeobox transcription factor 1, beta (LMX1B) genes, have yet to be assessed as genetic susceptibility factors for POAG. This evidence concerns the gene LMX1B and open-angle glaucoma.