A recent genome-wide association study involving 590 affected individuals with advanced POAG and 3,956 controls, has identified susceptible loci at transmembrane and coiled-coil domain-containing protein 1 (TMCO1) and CDKN2B antisense RNA 1 (non-protein coding; CDKN2B-AS1) for POAG [22]. This evidence concerns the gene TMCO1 and open-angle glaucoma.