In NHANES 2005–2006, 68% of children 6–10 years of age with reported eczema did not have sensitization to indoor allergens, and 36% did not have elevated (i.e., > 50 IU/mL) total IgE levels (NCHS 2008), compared with 71% and 40% respectively at 60 months of age in this African-American and Dominican cohort. This evidence concerns the gene IGHE and Eczematoid dermatitis.