Fourrier F, Chopin C, Goudemand J, Hendrycx S, Caron C, Rime A, Marey A, Lestavel P: Septic shock, multiple organ failure, and disseminated intravascular coagulation - compared patterns of antithrombin-III, protein-C, and protein-S deficiencies. Chest 1992, 101:816-823. The gene discussed is PROS1; the disease is Multiple Organ Failure.