To assess the contribution of osteoclast signaling molecules in osteoclastogenesis in RANKL-primed RAW-D cells induced by infection with P. gingivalis, we analyzed mRNA expression levels of NFATc1, c-Fos, and IFNβ in unprimed RAW-D cells treated or not treated with RANKL or P. gingivalis, and in RANKL-primed RAW-D cells retreated or not retreated with RANKL or P. gingivalis. This evidence concerns the gene NFATC1 and infection.