Initial analysis of the overall data regardless of cancer subtype showed that high NuMA levels increased with tumour grade (from 20.3% for grade 1 tumours to 24.1% for grade 3 tumours, p = 0.0016) and disease stage (an increase from 19.6% for stage 1 to 33.3% for stage 4, p = 0.0077) (data not shown). Here, NUMA1 is linked to cancer.