Multiple forms of RHAMM are overexpressed in a broad variety of solid tumors such as endometrial carcinoma [17], breast cancer [18], pancreatic cancer [19], stomach cancer [20], squamous cell lung carcinoma [21], and malignant melanoma [22], as well as in hematological malignancies like AML, MDS, B-CLL, and multiple myeloma [23, 24]. This evidence concerns the gene HMMR and acute myeloid leukemia.