Most of the pathways enriched in M1 are directly related to biological processes in asthma, including ‘Asthma’, ‘Cell adhesion molecules (CAMs)’, ‘Antigen processing and presentation’, ‘Cytokine-cytokine receptor interaction’, ‘Toll-like receptor signaling pathway’, ‘PPAR signaling pathway’, ‘Leukocyte transendothelial migration’ and ‘Chemokine signaling pathway’. The gene discussed is PPARA; the disease is asthma.