A study of inbred consanguineous populations from North African countries recommended investigating IL-12RB1 deficiency in patients with severe tuberculosis whether or not adverse effects of BCG vaccination or atypical mycobacteriosis were observed.16 One of the cases suffered recurrent attacks of Salmonella enteritidis, a finding reported in several other studies.17,18. The gene discussed is IL12RB1; the disease is tuberculosis.