Figure 1 demonstrates a Western blot analysis revealing CKIε to be overexpressed in 15 of 17 ovarian cancer cell lines, when compared with normal human ovarian surface epithelial (HOSE) cells. Further comparison of CKIε, CKIδ and CKIα expression patterns in ovarian cell lines showed that only one out of eight cancer cell lines had moderate CKIδ expression, two out of eight ovarian cancer cell lines showed overexpression of CKIα relative to the normal HOSE cells (Supporting Information Fig S2). Here, CSNK1E is linked to cancer.