In another recent study, Verma et al. [25] compared 85 HIV/HCV co-infected and 296 HCV-monoinfected patients during a period of 10 years, and demonstrated that patients taking HAART as the first antiretroviral regimen had an FPR similar to HCV-monoinfected subjects; HAART, but not CD4+ cell count or HIV RNA level, was independently related to liver fibrosis. Here, CD4 is linked to Hepatic fibrosis.