The tumor volumes were 3,620 ± 318 mm3, 697 ± 182 mm3, and 2,288 ± 301 mm3, and the median PSA values of the mice were 189.2 ng/mL, 4.3 ng/mL and 68.7 ng/mL for the AD, ND, and CR stages, respectively. The gene discussed is KLK3; the disease is neoplasm.