In accordance to our results, recent studies showed reduced CD11b expression and inhibition of CD11b-dependent monocyte adhesion to endothelium by HMG-CoA reductase inhibitors [44] Similarly, atorvastatin treatment led to a significantly lower expression of CD40L, CD11b and CD54 on monocytes and neutrophils in patients with coronary heart disease [45]. The gene discussed is ICAM1; the disease is coronary artery disorder.