In HF (n = 36) as a whole, mRNA expression for TPCN1 (p = 0.018), TPCN2 (p = 0.001) and IP3R1 (p = 0.035) was also increased relative to CTL (Table 3 and Figs. 3 and 4). This evidence concerns the gene TPCN2 and hydrops fetalis.