These studies confirmed the association of HLA alleles with renal diseases as HLA-DQ alpha 1 chain in idiopathic membranous nephropathy [43], HLA-DRB1 and HLA-DQB1 in hepatitis B virus induced nephropathy [44], HLA-DQ and HLA-B in IgA nephropathy [45]. The gene discussed is HLA-B; the disease is Nephropathy.