Among organ failure items, "severe AKI" had higher serum bilirubin values than "No AKI" (p = 0.00044) and "mild AKI" (p = 0.074), a lower prothrombin values than "no AKI" (p = 0.0029) and "mild AKI" (p = 0.0024), a lower platelet count than "no AKI" (p = 0.0038) and a lower mean arterial pressure than "no AKI" (p = 0.00011) and "mild AKI (p = 0.00053) (Tables 1 and 3). The gene discussed is F2; the disease is acute kidney injury.