The RASSF1A A133S SNP has been found in 20.6% of patients with breast carcinomas [23, 29], 19.8% in lung cancer [29, 32], 11.1% in head and neck cancer [32], 6.9% in colorectal cancer [32], 14.3% in esophageal cancer [32], 24.3% in patients with fibroadenoma and in 2.9%–10% of healthy controls [23, 32]. The gene discussed is RASSF1; the disease is lung cancer.