In the above mentioned study by Hlavata et al. [11], no such association was observed for Ile105Val polymorphism in GSTP1 locus (OR 1.01, 95%CI, 0.77 to 1.32, P = 0.944), but a similar trend for the GSTM1 deletion and its association with CRC risk was observed (OR 1.30, 95% CI 1.01 to 1.68, P = 0.044), which can be easily explained by the similar ethnic origin of both the cohorts [11]. This evidence concerns the gene GSTM1 and colorectal carcinoma.