These findings are in line with a variety of studies showing that a high survivin expression is correlated with increased risk of tumor recurrences, lymph node metastases and lower survival after definitive radiotherapy or chemoradiation in esophageal [25], cervical [26], lung [27], early (T1/T2) prostate [9], and in nasal/paranasal sinus cancer [28]. The gene discussed is BIRC5; the disease is metastatic malignant neoplasm in the lymph nodes.