A total of 15 variables were included: age, BMI, seven ultrasonographic variables (maximum tumor size, tumor depth/width ratio, multifocality, echogenic halo, interruption of the anterior border of the mammary gland, maximum size of lymph nodes, and a loss of hilum in lymph nodes), two mammographic variables (shape and distribution of calcification), two physical examination variables (skin dimpling and nipple discharge) and two pathological variables (histological/nuclear grade, HER2 status). This evidence concerns the gene ERBB2 and neoplasm.