However, tumors have developed a number of different strategies to escape immune surveillance, such as the loss of tumor antigen expression, the expression of Fas ligand (Fas-L) or CD200 that can induce apoptosis in activated T cells, the secretion of immunosuppressive cytokines, such as IL-10 or TGF-β, or the generation of regulatory T cells, and MHC downregulation or loss [19]. Here, FASLG is linked to neoplasm.