Because Arid4b was identified as a candidate gene in part based on differential expression between high and low metastatic strains of mice in the AKXD panel, and because Arid4b expression levels were associated with tumor growth and metastasis in mice as well as the activity of the metastasis-associated TPX2 network, we tested whether ARID4B expression alone correlated with human patient outcomes. Here, TPX2 is linked to neoplasm.