in a genetic analysis of the association between serum lipid levels and hepatic steatosis in CHC patients, Clark and coworkers identified 4 ingle nucleotide polymorphism (SNPs) in the IL28B gene region that were significantly associated with pretreatment LDL (top SNP rs12980275, P = 10-17, good IFN response variant = higher LDL). This evidence concerns the gene IFNL3 and cryohydrocytosis.