In this way, it also inhibits phosphorylation of the protein tau (which is hyperphosphorylated in Alzheimer’s disease) with promising potential against human neurodegenerative diseases [77], and NF-κB activity, probably by inhibiting both protein kinase C and I-kB phosphorylation [78]: molecules able to interfere with factors involved in the modulation of gene expression, such as NF-κB, can also be considered as potential anti-inflammatory agents. The gene discussed is NFKB1; the disease is early-onset autosomal dominant Alzheimer disease.