Regarding the role of PCT in IFIs, the literature data are still few and controversial (Charles et al. 2009; Christofilopoulou et al. 2002; Huber et al. 1997); mostly, late elevations of PCT have been observed in patients with disseminated aspergillosis (Beaune et al. 1998) and in some children with invasive candidiasis (Dornbusch et al. 2005). Here, CALCA is linked to Candidiasis, Invasive.