CASP3 and serum lipopolysaccharide activity: We have detected elevated level of caspase-3 protein in the acini isolated from animals subjected to the endotoxemia in the infancy due to increasing doses of LPS (5, 10 or 15 mg/kg/day × 5 days) with the ratio of caspase-3/GAPDH reaching 113.0 ± 0.4 (Figure 12).