Considering that LFVC was associated with ST-T abnormalities independently of cardiometabolic factors, circulating CRP, diabetes, and MetS, which are proatherosclerotic and proinflammatory [9, 10], several factors not examined in this study, such as insulin resistance, oxidative stress, or subclinical hypoxia, might interfere with the relationship between LFVC and ST-T abnormalities. The gene discussed is INS; the disease is diabetes mellitus.