CK19 is an epithelial marker, which, when identified in lymph nodes from patients with colorectal cancer, is highly suggestive of the presence of lymph node metastases.12-14 OSNA was used previously for the detection of breast cancer12-17 and gastric cancer18; however, currently, the data are very limited regarding the detection of colon cancer lymph node metastases.19, 20. Here, KRT19 is linked to metastatic malignant neoplasm in the lymph nodes.