BCL2 and cancer: Bcl-2 has been found overexpressed not only in B-cell lymphomas, but also in a variety of other cancers such as: Hodgkin lymphoma where it seems to be associated with worse overall survival [19]; breast cancer where it correlates with tumor aggressiveness, reduced survival and resistance to endocrine therapy [20]; non-small and small cell lung carcinoma (moreover squamous) [21], renal cell carcinoma [22].