Also, U2AF65 expression was highly significantly correlated with p54nrb expression in both normal and tumor nuclear extracts (p = 0.00037 and 1e-6, respectively)(Table3b), but with PSF expression only in tumor nuclear extracts (p = 0.0005), suggesting a unique functional aspect of U2AF65 and PSF in tumor cell nuclei. Here, U2AF2 is linked to neoplasm.