Even more Mac3+ cells were found in cardiac tissue of CVB3-infected STAT3 KO mice compared to CVB3-infected WT mice (WT: 3.72 ± 1.29 fold versus STAT3 KO: 8.86 ± 2.12 fold, P = 0.0232) 28 days after infection. The gene discussed is STAT3; the disease is infection.