Table 1 shows the comparison of clinical, biochemical, and histopathological characteristics of patients with and without steatosis. Patients with steatosis had a significantly higher AFP (P < 0.001) and necroinflammation and fibrosis/cirrhosis (P < 0.001). Also AST (P < 0.001), ALT (P = 0.002), total Bilirubin (P = 0.023), and prothrombin time (P = 0.003) were significant high in chronic HCV with steatosis than without steatosis. This evidence concerns the gene F2 and Cirrhosis.