So far, 15 FA genes (FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ, FANCL, FANCM, FANCN/PALPB2, FANCO/RAD51C, and FANCP/SLX4) have been identified that can be mutated in FA [2, 10–12], of which FANCA, FANCG, and FANCC are the most commonly mutated genes in studied FA populations [2]. The gene discussed is FANCE; the disease is Friedreich ataxia.