Although this abnormal expression pattern could conceivably be a cause or an effect of progressive BMF, subsequent work established that FA-deficient hematopoietic progenitor cells were subject to an inhibition of proliferation and increased apoptosis following treatment with TNF-α, IFN-γ, and MIP-1-α [27, 29, 125–127]. Here, TNF is linked to Friedreich ataxia.