All studies in obese NGT [45, 51, 53], obese impaired glucose tolerant (IGT) [54], or obese T2DM patients [43, 52] consistently showed increased insulin sensitivity with no differences between diet-only or diet with exercise group (with the exception of [45] all measured with the hyperinsulinaemic euglycaemic clamps). Here, INS is linked to Impaired glucose tolerance.