Indeed, analysis of IL-10 and TGF-β1 expression status in lymph nodes and tumors using qRT-PCR revealed strong IL-10 and TGF-β1 mRNA expression in tumor-draining lymph nodes in high tumor-burdened LLA-TG-3 mice compared to the low tumor burden group (Fig. 6a). The gene discussed is TGFB1; the disease is neoplasm.