Cerebral aneurysm can occur due to the development of chronic inflammation mediated by nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB),35 which is induced by oxidative stress.36 Cerebral aneurysms in antioxidant-treated rats were 54% smaller than in controls, due to inhibition of NF-κB activity.37 The gene discussed is NFKB1; the disease is brain aneurysm.