The Kaplan-Meier plot showed that the patients with overexpression of neogenin had more low-grade glioma rate (71.4% versus 26.5%) and longer tumor latency (1187.6±162.6 days versus 687.4±254.2 days) (n = 69, p<0.001, Fig. 4). Here, NEO1 is linked to neoplasm.