However, many pieces of evidence have shown that other SNPs in these genes like TNF–308 G>A (rs1800629), LTA 252A>G (rs909253), IL10–3575T>A (rs1800890), LEPR 233Q>R (rs1137101) increased the risk of NHL, particularly DLBCL in non-Hispanic white populations [9], [14], [15], [32], [33]. The gene discussed is TNF; the disease is diffuse large B-cell lymphoma.