Indeed, EGF-induced EMT in MDA-MB-468 breast cancer cells is associated with a remodeling of purinergic receptor-mediated Ca2+ signaling [19] and transforming growth factor β (TGFβ)-induced EMT in MCF7 breast cancer cells has been reported to be associated with increased store-operated Ca2+ influx [20]. Here, EGF is linked to breast carcinoma.