Evaluation of the total amount of TNF receptors by ELISA in spleen homogenates revealed that TNFR1 and TNFR2 levels were lower at 2 weeks infection in memTNFΔ1–12 KI mice, but were significantly increased at 4 weeks infection when mice showed disease symptoms (Fig. 7C, D). This evidence concerns the gene TNFRSF1A and infection.