Some of the proteins with MYND domain include BS69, a transcriptional corepressor; the chimeric fusion protein of acute myelogenous leukemia (AML) and ETO (a nuclear protein that interacts with corepressor molecules) (AML-1-ETO); the bone morphogenesis protein receptor-associated molecule 1 (BRAM1), deformed epidermal autoregulatory factor-1 (DEAF-1), and SET and MYND domain-containing proteins (SMYD) [124–126]. This evidence concerns the gene RUNX1 and acute myeloid leukemia.