Mutations in Crumbs homolog 1 (CRB1), Lecithin retinol acyltransferase (LRAT), Mer tyrosine kinase protooncogene (MERTK), Retinal pigment epithelium-specific protein, 65-KD (RPE65), Spermatogenesis-associated protein 7 (SPATA7), and TULP1 have been identified in individuals with LCA and arRP [18-21,34-47]. This evidence concerns the gene SPATA7 and Leber congenital amaurosis.