Previously, there have not been additional genetic markers associated with risk of disease in both the breast and the ovary besides BRCA1 and BRCA2. However, a functional germline variant in the 3′UTR of the KRAS oncogene (rs61764370) has been recently identified and reported to be associated with increased risk of both invasive epithelial ovarian cancer [9] and breast cancer [10] in clinically well-annotated cohorts. This evidence concerns the gene BRCA1 and breast carcinoma.