Carriage of one or more mutant alleles in combined carriership of TLR4+896 and TLR9 -1237 increases the risk for hearing loss in BM patients (p  = 0.0006, OR 4.1, 95% CI 1.8–9.4, in MM patients: p  = 0.02, OR 4.3 95% CI 1.3–14.2, in PM patients: p  = 0.003, OR 6.0, 95% CI 1.7–21.3). Here, TLR4 is linked to sensory perception of sound.