To further support this issue, renal biopsy showed chronic mesangial IgA glomerulonephritis and no evidence of lipid deposits in the kidney, a picture clearly different from the typical form of renal damage observed in subjects with genetic LCAT deficiency, that is focal glomerulosclerosis with vacuolization of glomerular basement membrane due to lipid deposition.10 Here, LCAT is linked to focal segmental glomerulosclerosis.