KATNAL1 and infection: Indeed, over-expression of the WT KATNAL1 protein in HT1080 cells significantly increased both the number of cells in mitosis (p<0.0001) and significantly increased overall cell death compared to vehicle or control lentivirus when tested at 48 hours post-infection (p<0.001), whereas over-expression of mutant Katnal11H cDNA failed to induce any increase in number of cells in mitosis or any change in overall cell death relative to controls (Figure 4).